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REVIEW ARTICLE
Year : 2012  |  Volume : 1  |  Issue : 4  |  Page : 217-223

Polymeric nanoparticles for drug delivery and targeting: A comprehensive review


1 Department of Pharmaceutics, JSS College of Pharmacy, Ootacamund, Tamil Nadu, India
2 Department of Pharmaceutical Analysis, JSS College of Pharmacy, Ootacamund, Tamil Nadu, India

Correspondence Address:
Natarajan Jawahar
Department of Pharmaceutics, JSS College of Pharmacy, Ootacamund - 643 001, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2278-344X.107832

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In the recent years, many modern technologies have been established in the pharmaceutical research and development area. The field of nanotechnology has been revolutionary as substantial and technical, and scientific growth, in basic sciences plus manipulation by physical or chemical process of individual atoms and molecules have widened its horizon. Polymeric nanoparticles with a size in the nanometer range protect drugs against in vitro and in vivo degradation; it releases the drug in a controlled manner and also offers the possibility of drug targeting. The use of polymeric drug nanoparticles is a universal approach to increase the therapeutic performance of poorly soluble drugs in any route of administration. The present review discusses the physico-chemical properties of polymeric nanoparticles, production methods, routes of administration and potential therapeutic applications.


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