Home Print this page Email this page
Users Online: 429
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2013  |  Volume : 2  |  Issue : 2  |  Page : 81-87

Microwave assisted synthesis, characterization and evaluation for their antimicrobial activities of some novel pyrazole substituted 9-anilino acridine derivatives


Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Ootacamund, Tamil Nadu, India

Correspondence Address:
Rajagopal Kalirajan
Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Ootacamund - 643 001, Tamil Nadu
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2278-344X.115682

Rights and Permissions

Objective: The paper focuses on the microwave synthesis of a new series of 9-anilinoacridine derivatives 4a-g, 5a-g, and 6a-g. Materials and methods: The compounds were confirmed by physical and analytical data. The synthesized compounds when screened for in vitro anti-microbial activity showed promising activity for many compounds. The in vitro anti-microbial activities of the synthesized compounds were evaluated against some bacteria and fungi strains. Results and Discussions: The results suggested that, the products 4a-g, 5a-g, and 6a-g exhibited good inhibitory effect against most of the tested organisms. Especially, 4b, 5a, 5d, 6b, and 6e were shown to be most effective against Bacillus subtilis, Escherichia coli at the concentration of 25 μg/ml and Candida albicans at the concentration of 50 μg/ml.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1783    
    Printed28    
    Emailed0    
    PDF Downloaded237    
    Comments [Add]    
    Cited by others 3    

Recommend this journal