SHORT COMMUNICATION |
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Year : 2015 | Volume
: 4
| Issue : 2 | Page : 115-118 |
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Correlation between homocysteine and Vitamin B12 levels: A post-hoc analysis from North-West India
Sunil Kumar Raina1, Jagjit Singh Chahal2, Navjot Kaur3
1 Department of Community Medicine, Dr. RP Government Medical College, Tanda, Himachal Pradesh, India 2 Department of Biochemistry, Dr. RP Government Medical College, Tanda, Himachal Pradesh, India 3 Department of Pathology, Dr. RP Government Medical College, Tanda, Himachal Pradesh, India
Correspondence Address:
Sunil Kumar Raina Department of Community Medicine, Dr. RP Government Medical College, Tanda, Himachal Pradesh India
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/2278-344X.154915
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Background: Homocysteine has been shown to be a risk factor for cardiovascular disease and is a degradation product of sulfur containing amino acids. The aim of this post-hoc analysis was aimed at arriving at homocysteine levels among voluntarily consenting healthy adults in the context of other hematological parameters. Methods: The data for this post-hoc analysis were derived from an observational study carried out at a medical college in rural North-west India. Results: About 77.42% of those participants enrolled in this study having serum homocysteine level more than 30 μmol/L were seen to possess suboptimal serum Vitamin B 12 (<200 pg/ml). On subjecting data to regression analysis, serum homocysteine was observed to possess an inverse correlation with serum level of Vitamin B 12, in general. Conclusions: Hyperhomocysteinemia observed in our study was sufficiently common and wholly ascribable to low Vitamin B 12 concentration as we did not find any case of subnormal serum folic acid level. |
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