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COMMENTARY
Year : 2020  |  Volume : 9  |  Issue : 5  |  Page : 111-113

COVID-19 infection: The prospects of pharmacotherapy


1 Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India
2 Department of Biotechnology, Teresian College, Mysuru, Karnataka, India
3 Department of Chemistry, The National Institute of Engineering, Mysuru, Karnataka, India
4 Department of Pharmacology, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India

Correspondence Address:
Dr. Ramith Ramu
Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru - 570 015, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijhas.IJHAS_89_20

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The disastrous outbreak of coronavirus disease 2019 (COVID-19) has triggered the investigation of several therapeutic options following the redundancy of specific drugs against it. The virus possesses advanced molecular mechanisms to effectively invade the host cell compared to its counterparts. It results in a seamless and coherent infection and transmission, attributing to its enhanced pathogenicity. The drugs that are currently being employed against COVID-19 inhibit the viral load in different stages of infection, including host cell–virus interaction, viral entry into the host cell, and viral replication inside the host including genome replication and polypeptide chain production. This commentary emphasizes the pharmacotherapeutic options available from the perspective of viral life cycle and pathogenicity.


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