TY - JOUR A1 - Gupta, M A1 - Nayak, Kartik A1 - Verma, Savita A1 - Arya, Siddharth T1 - Disulfiram-induced hyperpigmentation Y1 - 2018/10/1 JF - International Journal of Health & Allied Sciences JO - Int J Health Allied Sci SP - 263 EP - 265 VL - 7 IS - 4 UR - https://www.ijhas.in/article.asp?issn=2278-344X;year=2018;volume=7;issue=4;spage=263;epage=265;aulast=Gupta DO - 10.4103/ijhas.IJHAS_44_18 N2 - Abnormal pigmentation of skin is a less morbid condition but can be more distressing to the patient and a major cause of psychological distress. Disulfiram is the first-line drug for the treatment of alcohol dependence. It inhibits acetaldehyde dehydrogenase resulting in accumulation of aldehyde component of ethanol metabolism leading to unpleasant effects. Disulfiram-induced dermatological disorders correspond to an intermediate rate of adverse reactions, and occurrence of hyperpigmentation is a very rare phenomenon. In this submission, we report a case of disulfiram-induced hyperpigmentation in a patient being treated for alcohol dependence. ER -