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ORIGINAL ARTICLE
Year : 2013  |  Volume : 2  |  Issue : 4  |  Page : 264-269

A review of postinfectious glomerulonephritis cases from a tertiary care renal referral center in South India


1 Department of Pathology, Institute of Nephrourology, Victoria Hospital Campus, Bangalore, Karnataka, India
2 Department of Biochemistry, Institute of Nephrourology, Victoria Hospital Campus, Bangalore, Karnataka, India
3 Department of Microbiology, Institute of Nephrourology, Victoria Hospital Campus, Bangalore, Karnataka, India

Correspondence Address:
Sujatha Siddappa
Department of Pathology, Institute of Nephrourology, Victoria Hospital Campus, Bangalore - 560 002, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2278-344X.126745

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Background: Postinfectious glomerulonephritis is an immune mediated renal disease and one of the causes for end stage renal disease in developing countries like India. The disease spectrum has changed significantly in the past few decades. The goal of this study is to review the prevalence and clinicopathological spectrum of the disease in a major tertiary care renal referral hospital. Materials and Methods: Between July 2007 and July 2012, 54 cases of postinfectious glomerulonephritis were identified at our medical center. The patients' records were retrospectively reviewed with respect to clinical presentation, laboratory, histopathology, and clinical course. Results: There were 32 males and 22 females. The mean age was 24.1 years. Twenty six percent of patients presented with acute renal failure and required dialysis support during the course of disease. Hypocomplementemia was present in about 90% of the patients. Histologically, characteristics showed distinct patterns of glomerulonephritis with predominant "starry sky pattern" on immunofluorescence. At the last follow-up, none of the patients were dialysis-dependent, and 53% were in complete remission. Conclusions: We hereby report cases of postinfectious glomerulonephritis with history of recurrence and cross infection to highlight the importance of treatment and awareness regarding this preventable cause of chronic renal disease.


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